3-Methylethergalangin Isolated from Alpinia officinarum Inhibits Pancreatic Lipase

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3-Methylethergalangin isolated from Alpinia officinarum inhibits pancreatic lipase.

The pancreatic lipase inhibitory activity of the rhizome of Alpinia officinarum (AO) and its antihyperlipidemic activity were measured. When the water extract of AO was fractionated stepwise with organic solvents, the ethyl acetate fraction exhibited the most potent inhibition. 3-Methylethergalangin was isolated from that fraction as an inhibitor of pancreatic lipase with an IC(50) value of 1.3...

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In vitro and in vivo anti-influenza virus activity of diarylheptanoids isolated from Alpinia officinarum.

BACKGROUND Diarylheptanoids (AO-0002 [7-(4''-hydroxy-3''-methoxyphenyl)-1-phenyl-4E-hepten-3-one] and AO-0011 [(5S)-5-hydroxy-7-(4''-hydroxyphenyl)-1-phenyl-3-heptanone]) isolated from Alpinia officinarum have been reported to exhibit anti-influenza virus activity in vitro. Hence, efficacies against influenza virus infection and the mode of antiviral action were evaluated in vivo and in vitro, ...

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Antioxidant and Antimicrobial Activity of Alpinia officinarum

Alpinia officinarum is a rhizome belonging to the family zingeberaeceae. Hydro alcoholic extract by hot and cold maceration and methanol extract by percolation process Qualitative phytochemical analysis of extract of Alpinia officinarum rhizome showed a majority of the compound including tannins, alkaloids, flavonoids and saponins. Hydroalcoholic extract prepared by hot maceration process was f...

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Inhibition of in vitro cytotoxic effect evoked by Alpinia galanga and Alpinia officinarum on PC - 3 cell line

Plants have been a source of medicine and a major resource for health care since ancient times, with some traditional herbal medicines having been in use for more than 2,000 years. Herbs and spices are recommended for prevention and cure of various diseases including cancer. Alpinia galanga and Alpinia officinarum, botanical cousin to ginger was recognized superior in many ways and has been emp...

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Antiarthritic Effect of Galangin Isolated from Rhizomes of Alpinia Officinarum in Complete Freund’s Adjuvant-induced Arthritis in Rats

Objective: The objective of the present study was to isolate galangin from methanolic extract of Alpinia officinarum (MEAO) by bioassay guided fractionation using hexane–ethyl acetate as a solvent and evaluated the anti-arthritic effect of galangin and MEAO in complete Freund’s adjuvant (CFA) induced arthritis in wistar rats. Methods: Arthritis was induced by intradermal injection of CFA into t...

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ژورنال

عنوان ژورنال: Biological and Pharmaceutical Bulletin

سال: 2003

ISSN: 0918-6158,1347-5215

DOI: 10.1248/bpb.26.854